Results
PMID | 17624340 |
Gene Name | PTPN22 |
Condition | Endometriosis |
Association |
Associated |
Mutation | PTPN22( *)T variant |
Sex | Female |
Infertility type | Female infertility |
Associated genes | PTPN22 |
Other associated phenotypes |
Endometriosis |
Fertil Steril. 2008 Apr;89(4):993-4. Epub 2007 Jul 10. Ammendola, Maria| Bottini, Nunzio| Pietropolli, Adalgisa| Saccucci, Patrizia| Gloria-Bottini, Fulvia Division of Gynecology and Obstetrics, Department of Surgery, Hospital University of Rome Tor Vergata, School of Medicine, Rome, Italy. PTPN22 is currently one of the few known shared-autoimmunity genes and is therefore a candidate marker for endometriosis. Our data show that female carriers of the PTPN22( *)T variant are significantly more susceptible to endometriosis than controls. Mesh Terms: Adult| Case-Control Studies| Endometriosis/enzymology/*genetics| Female| Gene Frequency| Genetic Predisposition to Disease| Humans| Italy| Male| *Polymorphism, Genetic| Protein Tyrosine Phosphatase, Non-Receptor Type 22/*genetics| Risk Factors| |